We screen any drugs on electrical pacemaker activities

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We use bio-electrical data to build drug databases

View drug databases

We apply our "electrial" drug databases to train Artificial Intelligence

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We utilize bio-electrical big-data to health and diseases

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Latest News

16-05-2024

Asia Summit on Global Health (16-17 May)

Exhibition

ASGH
06-03-2024

25 New Drugs were added into GIPADD!!

Gut Rhythm

Link to database
11-01-2024

Guideline Video on How to Use Gut Rhythm Drug Database (Ver 1.1)

Youtube

Video link
05-01-2024

2nd round Beta-Testing of Drug Database

Gut Rhythm

Link to User Experience Report (Google Form)
23-09-2023

Received the Most Popular Award at the CUHK Entrepreneurship Competition

CUHK Entrepreneurship Day 2023

Link to event
23-09-2023

Received the Creative Award at the CUHK Entrepreneurship Competition

CUHK Entrepreneurship Day 2023

Link to event
21-09-2023

Received the Most Innovative Technology Award at the Elevator Pitch Competition

CUHK Innovation Day 2023

Link to event
01-08-2023

Entered the Top 5 at the CUHK Entrepreneurship Competition

CUHK Alumni Association

Promotional Video
02-07-2023

Presented at the 19th World Congress of Basic & Clinical Pharmacology in Glasgow, Scotland

WCP2023 (BJP, IUPHAR)

Link to event
17-05-2023

Asia Summit on Global Health (ASGH) (17 – 18 May 2023)

ASGH organized by HKTDC & HKSAR

Link to event
15-03-2023

Received Technology Start-up Support Scheme for Universities 2023-24

Funding

Link to Fund
07-03-2023

Non-provisional US patent and China patent filed for application

Patent

Gut Rhythm
22-02-2023

Received Knowledge Transfer Project Fund to support the development of our website based bio-electrical drug database

Funding

Link to Project
21-12-2022

Gut rhythm R&D (Hong Kong) Limited incorporated at the Company Registry of the Hong Kong SAR

Company Incorporation

Gut Rhythm
20-01-2022

Our work on uterine slow potentials received Strategic Partnership Award for Research Collaboration between the Chinese University of Hong Kong and the University of Auckland

Collaboration Award

Gut Rhythm
07-03-2022

Provisional US patent filed

Provisional Patent

Gut Rhythm

Co-founders

Professor John Anthony RUDD

Professor John Anthony RUDD

Chief Scientific Advisor

John is a Professor at the School of Biomedical Sciences, at the Chinese University of Hong Kong (CUHK). He has continued his service at CUHK for almost 30 years. He has a Ph.D. in Pharmacology (University of Bradford, 1991) and worked on anti-emetic research for over 30 years. He collaborated with 27 pharmaceuticals in drug discovery projects. He introduced >90M research funding to academia. His research team currently has 10 research staff and PhD students.

Visit JAR laboratory website
Dr. Julia Yuen Hang LIU

Dr. Julia Yuen Hang LIU

Chief Executive Officer

Julia is a Research Associate at the School of Biomedical Sciences, CUHK. She graduated with a Ph.D. in Biomedical Sciences (CUHK, 2017), worked on Alzheimer's diseases, and simultaneously worked on a side project to develop an efficient technology to record gut bio-electrical signals from small animals. Up to 2022, she has 16 publications, nine of which are in the bio-electrical research field. She began the path to commercialize the technology in 2020 and became one of the co-founders of Gut Rhythm.

Our Services

Drug Testing Service

Drug Testing Service

We create unique 'bio-electrical' drug profile for any drugs, food supplements, traditional remedies, probiotics, basically any chemical entities in a week! This drug testing report can be matched with our drug database for predicting potential drug effects and drug adverse effects using artificial intelligence!

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Database Subscription

Database Subscription

An interactive platform to access our Gastrointestinal Pacemaker Activity Drug Database (GIPADD) to perform drug-to-drug comparison on bio-electrical data resources has been launched in Jan 2024. This database contains electrical profile for >190 drugs, based on >12,000 experimental datasets.

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Drug Predictions

Drug Predictions

Our first-generation artificial intelligence product can predict >20 drug adverse effects with >90% precision, including vomiting, nausea, diarrhoea, abdominal pain, oedema, dermatitis, rash, dizziness, etc.

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Our Latest Research

01-11-2023

Predict Drug-induced Nausea with Deep Learning using a new Gastro-Intestinal Pacemaker Activity Drug Database (GIPADD)

Poster Presentation at the Safety Pharmacology in the 21st Century

Link to Poster
01-04-2023

Predicting drug adverse effects using a new Gastro-Intestinal Pacemaker Activity Drug Database (GIPADD)

Scientific Reports

Nature Link
01-02-2023

Regional differences of tachykinin effects on smooth muscle and pacemaker potentials

Neuropeptides

Pubmed Link
01-12-2021

Chemotherapy drugs, cisplatin-induced emesis, gut dysrhythmia, cardiac and respiratory dysfunction

Frontiers in Pharmacology

Pubmed Link
01-04-2021

Role of TRPV1 and TRPA1 in pacemaker potentials in the mouse ileum​

Cell Calcium

Pubmed Link
01-11-2021

Automatic program-based analytical pipeline to analysis gut pacemaker activity

IEEE EMBC

Pubmed Link
01-07-2020

Novel acetylcholine inhibitory and excitatory effects on the mouse ileal pacemaker activity

Am J Physiol Gastroin Liver Physiol

Pubmed Link
01-06-2019

Use of microelectrode array to record gastrointestinal pacemaker activity

Cell Calcium

Pubmed Link

Patents

7 March 2021 SYSTEMS AND METHODS TO EVALUATE DRUG-INDUCED GASTROINTESTINAL DYSRHYTHMIA (Provisional US Patent: 63/268,957) 
7 March 2022 SYSTEMS AND METHODS TO EVALUATE DRUG-INDUCED GASTROINTESTINAL DYSRHYTHMIA (Non-provisional US Patent 18/179,583)
7 March 2022 評估誘發藥物的胃腸節律障礙的系統和方法
(China patent: 2023102158201)